Ian Green, Chief Executive of Terrence Higgins Trust, said: 'Our thoughts are with the Queen’s children, grandchildren and the wider Royal Family as they – and the country – reflect on a life lived in dedicated service.

'Her immense support for charities and good causes has been a hallmark of her reign. She has worked to tackle HIV stigma and support HIV care through her domestic and Commonwealth duties. Whether it is meeting a London-based patient with an AIDS-related illness in 1989, opening the Mildmay HIV Centre in Kampala, Uganda in 2007, or visiting an AIDS memorial garden in 2015, she has taken her message of compassion to a global audience time and again.

'Today, we join with those around the globe mourning her passing and add our tributes to an unparalleled public servant.'